Shoji Tsuji Selected Research

Parkinson Disease (Parkinson's Disease)

1/2019	Neuroimaging, genetic, and enzymatic study in a Japanese family with a GBA gross deletion.
1/2019	Increased facilitation of the primary motor cortex in de novo Parkinson's disease.
4/2015	Variants associated with Gaucher disease in multiple system atrophy.
1/2014	Triad-conditioning transcranial magnetic stimulation in Parkinson's disease.
11/2010	CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease.
7/2010	Multiplexed resequencing analysis to identify rare variants in pooled DNA with barcode indexing using next-generation sequencer.
4/2006	Pathology of the sympathetic nervous system corresponding to the decreased cardiac uptake in 123I-metaiodobenzylguanidine (MIBG) scintigraphy in a patient with Parkinson disease.
6/2005	An LRRK2 mutation as a cause for the parkinsonism in the original PARK8 family.
10/2003	Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies.
3/2002	Immunocytochemical localization of synphilin-1, an alpha-synuclein-associated protein, in neurodegenerative disorders.

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Shoji Tsuji Research Topics

Disease

12	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2022 - 10/2004
11	Neoplasms (Cancer) 03/2024 - 01/2003
11	Multiple System Atrophy 05/2023 - 03/2002
10	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 03/2002
10	Parkinsonian Disorders (Parkinsonism) 01/2023 - 03/2002
10	Parkinson Disease (Parkinson's Disease) 01/2019 - 03/2002
9	Nephrotic Syndrome (Syndrome, Nephrotic) 09/2021 - 05/2009
9	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 10/2019 - 12/2003
8	Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy) 09/2023 - 05/2002
8	Alzheimer Disease (Alzheimer's Disease) 11/2017 - 07/2004
7	Dementia (Dementias) 11/2022 - 03/2002
7	Infections 01/2021 - 07/2003
6	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 07/2022 - 03/2005
6	Proteinuria 01/2018 - 09/2011
5	Urinary Tract Infections (Urinary Tract Infection) 08/2022 - 09/2015
5	Huntington Disease (Huntington's Disease) 01/2022 - 03/2004
5	Nocturnal Enuresis (Bedwetting) 09/2021 - 01/2018
5	Muscle Weakness 06/2015 - 06/2012
4	Ataxia (Dyssynergia) 03/2024 - 07/2014
4	Muscular Diseases (Myopathy) 10/2023 - 12/2016
4	Atrophy 01/2023 - 09/2006
4	Dysbiosis 01/2023 - 01/2018
4	Demyelinating Diseases (Demyelinating Disease) 01/2020 - 06/2002
4	Epilepsy (Aura) 01/2018 - 09/2010
4	Pain (Aches) 07/2016 - 01/2003
4	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 06/2013 - 09/2009
3	Peripheral Nervous System Diseases (PNS Diseases) 03/2024 - 10/2013
3	Gaucher Disease (Gaucher's Disease) 08/2023 - 01/2013
3	Intellectual Disability (Idiocy) 01/2023 - 04/2014
3	Cicatrix (Scar) 08/2022 - 09/2015
3	Hereditary Spastic Paraplegia 07/2022 - 02/2012
3	Myositis (Idiopathic Inflammatory Myopathies) 01/2022 - 06/2012
3	Glomerulonephritis 01/2021 - 05/2007
3	Encephalitis (Encephalitis, Rasmussen) 10/2018 - 08/2010
3	Guillain-Barre Syndrome 01/2018 - 07/2003
3	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 02/2015 - 04/2012
3	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 09/2014 - 02/2004
3	X-Linked Bulbo-Spinal Atrophy 06/2013 - 01/2006
3	Chronic Granulomatous Disease 10/2012 - 06/2002
2	Paraneoplastic Cerebellar Degeneration 03/2024 - 01/2006
2	Mitochondrial Diseases (Mitochondrial Disease) 12/2023 - 07/2022
2	Myoclonic Epilepsies (Myoclonic Encephalopathy) 09/2023 - 06/2023
2	Inflammation (Inflammations) 01/2023 - 06/2012
2	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 01/2023 - 01/2020
2	Kidney Diseases (Kidney Disease) 07/2022 - 01/2013
2	Paraplegia (Spastic Paraplegia) 07/2022 - 02/2012
2	Acute Kidney Injury (Acute Renal Failure) 07/2022 - 01/2021
2	Polymyositis 01/2022 - 05/2007
2	Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy 11/2021 - 04/2009
2	Chronic Disease (Chronic Diseases) 08/2021 - 06/2012
2	Vesico-Ureteral Reflux (Vesicoureteral Reflux) 01/2021 - 12/2020
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2021 - 10/2005

Drug/Important Bio-Agent (IBA)

19	Proteins (Proteins, Gene)FDA Link 06/2023 - 03/2002
15	polyglutamineIBA 09/2014 - 05/2002
11	DNA (Deoxyribonucleic Acid)IBA 07/2022 - 12/2003
8	Biomarkers (Surrogate Marker)IBA 01/2023 - 10/2011
8	AntibodiesIBA 10/2018 - 03/2002
6	CreatinineIBA 07/2022 - 09/2015
6	SteroidsIBA 01/2021 - 06/2002
5	RNA (Ribonucleic Acid)IBA 12/2023 - 11/2013
5	alpha-SynucleinIBA 01/2022 - 03/2002
5	Amyloid (Amyloid Fibrils)IBA 01/2019 - 07/2004
4	coenzyme Q10 (CoQ10)IBA 05/2023 - 01/2016
4	16S Ribosomal RNAIBA 01/2023 - 01/2012
4	NucleotidesIBA 01/2020 - 11/2009
4	Glucosylceramidase (Glucocerebrosidase)IBA 01/2019 - 07/2010
4	Creatine Kinase (Creatine Phosphokinase)IBA 01/2018 - 06/2012
4	AutoantibodiesIBA 12/2016 - 01/2006
4	Superoxide Dismutase-1IBA 10/2015 - 10/2004
4	Immunoglobulin G (IgG)IBA 07/2013 - 10/2004
4	Intravenous Immunoglobulins (IVIG)FDA Link 06/2013 - 10/2004
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2012 - 12/2002
3	Nonsense Codon (Nonsense Mutation)IBA 03/2024 - 12/2012
3	EnzymesIBA 05/2023 - 06/2012
3	Butyrates (Butyrate)IBA 01/2023 - 01/2021
3	Levodopa (L Dopa)FDA LinkGeneric 01/2023 - 12/2006
3	PrebioticsIBA 01/2023 - 01/2019
3	Low Density Lipoprotein Receptor-Related Protein-2IBA 08/2022 - 01/2017
3	Anti-Bacterial Agents (Antibiotics)IBA 12/2021 - 11/2012
3	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 09/2021 - 01/2020
3	AntioxidantsIBA 09/2021 - 06/2012
3	Butyric Acid (Butanoic Acid)IBA 08/2021 - 01/2018
3	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 12/2020 - 06/2002
3	Rituximab (Mabthera)FDA Link 01/2020 - 05/2008
3	Monoclonal AntibodiesIBA 01/2018 - 05/2008
3	Messenger RNA (mRNA)IBA 01/2014 - 01/2006
3	Brain Natriuretic Peptide (Natrecor)FDA Link 08/2013 - 12/2011
3	Immunoglobulins (Immunoglobulin)IBA 01/2013 - 05/2007
3	AntigensIBA 08/2010 - 02/2009
2	ubiquinolIBA 05/2023 - 01/2017
2	Apolipoproteins E (ApoE)IBA 11/2022 - 05/2009
2	HLA-DRB1 Chains (HLA DRB1)IBA 12/2021 - 11/2008
2	Oxidants (Oxidizing Agents)IBA 09/2021 - 10/2012
2	Myelin P0 Protein (Myelin Protein Zero)IBA 01/2021 - 01/2012
2	Cystatin CIBA 01/2021 - 01/2021
2	Vasopressins (Vasopressin)IBA 06/2020 - 01/2020

Therapy/Procedure

17	Therapeutics 01/2020 - 06/2002
4	Transcranial Magnetic Stimulation 04/2022 - 10/2010
3	Drug Therapy (Chemotherapy) 01/2021 - 10/2005
2	Hematopoietic Stem Cell Transplantation 08/2023 - 10/2005